Publications
publications by categories in reversed chronological order. generated by jekyll-scholar.
2025
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Pleiotropic heritability quantifies the shared genetic variance of common diseasesmedRxiv, 2025
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Metabolic reaction fluxes as amplifiers and buffers of risk alleles for coronary artery diseaseMolecular Systems Biology, 2025
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The contribution of genetic determinants of blood gene expression and splicing to molecular phenotypes and health outcomesNature Genetics, 2025
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Metabolic reaction fluxes as amplifiers and buffers of risk alleles for coronary artery disease2025
2024
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Integrated clinical risk prediction of type 2 diabetes with a multifactorial polygenic risk scoremedRxiv, 2024
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Aladyn Individual: Bayesian Hierarchical Dynamic Genetic Modeling of Comorbidity ProgressionmedRxiv, 2024
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Amplification and buffering of disease risk alleles by metabolic reaction fluxesIn EUROPEAN JOURNAL OF HUMAN GENETICS, 2024
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Genetic prediction of UK Biobank proteomics data for the OmicsPred portalIn EUROPEAN JOURNAL OF HUMAN GENETICS, 2024
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Enhancing 10-year cardiovascular disease prediction using polygenic risk scores and metabolomic biomarker scoresIn EUROPEAN JOURNAL OF HUMAN GENETICS, 2024
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Genetic regulators of whole blood gene expression and splicing and their impact on molecular traits and complex diseasesIn EUROPEAN JOURNAL OF HUMAN GENETICS, 2024
2023
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Age-dependent topic modeling of comorbidities in UK Biobank identifies disease subtypes with differential genetic riskNature Genetics, 2023
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Topic modeling identifies novel genetic loci associated with multimorbidities in UK BiobankCell Genomics, 2023
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Cardiovascular risk prediction using metabolomic biomarkers and polygenic risk scores: A cohort study and modelling analysesmedRxiv, 2023
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Genetic determinants of blood gene expression and splicing and their contribution to molecular phenotypes and health outcomesmedRxiv, 2023
2022
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Longitudinal modelling of genetic risk for common diseasesUniversity of Oxford (United Kingdom), 2022
2021
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The impact of age on genetic risk for common diseasesPLoS Genetics, 2021
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Modelling the impact of rapid tests, tracing and distancing in lower-income countries suggest that optimal policies vary with rural-urban settings2021